I wanted to try to create a new self portrait, and at f/1.8 with only a timer and manual focus, I can tell you it was a challenge.
Taken with a nikon D3s, 85mm F/1.8, and three SB900s
The first flash is a commander on the camera.
The second is in a Lastolite softbox on a C-stand over head and angled toward me.
the last SB900 is on a stand behind me and throwing a lot of light at the wall to wash it out.