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A major depressive episode is characterized by either feelings of sadness or a loss of interest that persists for at least two weeks and causes difficulties in an individual’s functioning at work, school, home, or in relationships with friends or family. Other common symptoms that might be present include:

  • A low mood for most of the day
  • Feelings of guilt
  • Feelings of worthlessness
  • Feeling nervous or anxious
  • Feeling slow and sluggish
  • Changes in appetite/weight loss or gain
  • Irritability or agitation
  • Trouble sleeping or sleeping too much
  • Decreased libido
  • Having trouble with concentration or memory


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